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Genminix Informatics Co Ltd
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CapitalBio Corporation
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Arraystar inc
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NimbleGen Systems GmbH
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imaGenes GmbH
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DataScience LTD
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Agendia BV
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Arraystar inc
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CH Instruments
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Image Search Results
Journal: BMC Ophthalmology
Article Title: MiRNAs regulate oxidative stress related genes via binding to the 3′ UTR and TATA-box regions: a new hypothesis for cataract pathogenesis
doi: 10.1186/s12886-017-0537-9
Figure Lengend Snippet: Heatmap shows differentially expressed mRNAs in cataractous lens samples compared with transparent lens samples. Six separate microarray assays were performed to determine the genome-wide mRNA expression in the central epithelium of transparent and cataractous human lenses. Microarray data were processed by CapitalBio Corporation. Heatmap shows differentially expressed mRNAs in cataractous lens samples compared with transparent lens samples. Relative expression value from high to low was shown by gradient of red to green in the heatmap. Colors indicate relative mRNA expression. Red and green indicate higher or lower expression of mRNAs relative to those in transparent lens samples, respectively. FDR (false discovery rate) adjusted p -value <0.05
Article Snippet:
Techniques: Microarray, Genome Wide, Expressing
Journal: Toxicological Sciences
Article Title: Chronic Hexavalent Chromium Exposure Upregulates the RNA Methyltransferase METTL3 Expression to Promote Cell Transformation, Cancer Stem Cell-Like Property, and Tumorigenesis
doi: 10.1093/toxsci/kfac023
Figure Lengend Snippet: Total RNA N6-methyladenosine (m6A) modification levels are significantly increased in chronic hexavalent chromium [Cr(VI)] exposure-transformed human bronchial epithelial cells and chronic chromate-exposed mouse lung tissues. A, The heatmap from m6A microarray analysis showing the extent of total messenger RNA m6A methylation in passage-matched control cells (BEAS-2B-Control) and chronic Cr(VI) exposure-transformed cells [BEAS-2B-Cr(VI)]. B and C, Relative total RNA m6A levels measured by using the EpiQuik m6A RNA Methylation Quantification Kit. The total RNA m6A levels in Cr(VI)-transformed cells (B) or chromate-exposed mouse lung tissues (C) are expressed relative to the passage-matched control cells (means ± SD, n = 3) (B) or vehicle control-exposed mouse lungs (means ± SD, n = 6) (C), respectively. *p < .05.
Article Snippet: The
Techniques: Modification, Transformation Assay, Microarray, Methylation, Control